Lesson 6 - Protein structure prediction
in Proteins Last modified at:
How to understand structure from sequence
Required reading for this lesson
- Video Nazim Bouatta - Machine learning for protein structure prediction, Part 1: Algorithm space
- Blogpost Carlos Outeiral Rubiera - AlphaFold 2 is here: what’s behind the structure prediction miracle
- Textbook Chapter on Protein Structure prediction (partly outdated, but section 7.21-7.23 on quaility criteria and section 7.3 on new frontiers in structure prediction are very informative)
Optional reading for this lesson
- Video Nazim Bouatta - Machine learning for protein structure prediction, Part 2: AlphaFold2 architecture
- Video Nazim Bouatta - Machine learning for protein structure prediction, Part 3: AlphaFold2 and OpenFold
- Blogpost Mohammed AlQuraishi - AlphaFold2 @ CASP14: “It feels like one’s child has left home.” Directly after CASP
- Blogpost Mohammed AlQuraishi - The AlphaFold2 Method Paper: A Fount of Good Ideas. When the AF2 paper was published
- Video Aleksa Gordić - Google DeepMind’s AlphaFold 2 explained
- Textbook chapter on Structure Determination (in case you want to learn more about the experimental techniques)
Slides
Video
Credits
The title image was taken from a blog post I have written as part of my consulting activities for PTNG. Also thanks to Mohammed AlQuraishi for allowing me to use some of his amazing figures in this lecture!
